Most of the time turning on "Optimize CSS files" in the performace section of Drupal works great. But, for some reason, having this option turned on was causing the jquery.cycle plugin to break only on the very first load of Internet Explorer. What was happening was that the second image to transition in was being resized to about 50x50px when it should have been something like 900x300px.
Dave Parrish
Freelance web page developer
